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Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: a randomised, open-label phase II trial

A fatty acid is attached to the lysine at position 20, increasing affinity for endogenous albumin, thereby extending its half-life and allowing for sustained therapeutic effects

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Kabata H, Moro K, Koyasu S

Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis
