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For more details, see the trial protocol in Supplement 1

Weight loss is not considered a medical necessity

Once completed, a healthcare provider will review your information and, if appropriate, prescribe your medication

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So it's not really apples-to-apples, but even said that on a like-for-like basis, comparing holiday 2024, to holiday 2023, we believe we had a very successful year in Local including some great numbers in the lead up to Christmas, and period between Christmas and New Year

These may include: Nausea, vomiting or diarrhoea (most common early on) Constipation Fatigue Mild increases in heart rate (similar to changes seen with GLP-1 medicines) Side effects were more frequent at higher doses (8 mg and 12 mg), but still rated mild to moderate overall