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Despite this, some medical centers, including Cedars-Sinai, advise patients to discontinue GLP-1RA use one week before elective procedures

Patients who have recently started taking a GLP-1 receptor agonist may be at greater risk of delayed gastric emptying than those who have been taking one of these medications for a longer period

[20] [21] These medications amplify these physiological effects by binding to GLP-1 receptors throughout the body, including in the pancreas, gastrointestinal tract, and brain regions that control appetite and satiety

Abbas T, Faivre E, Hlscher C (2009 Dec 14) Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimers disease

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MDL 3094 In Re: Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RAS) Products Liability Litigation