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Description
Diabetic ketoacidosis (DKA) risk is a serious concern, particularly for patients using insulin or SGLT2 inhibitors with very-low-carbohydrate diets

Initial availability is expected through specialty clinics, with broad pharmacy access following 3 to 12 months post-approval
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Davis, D
The SURPASS1-6 trials reported to date have clearly demonstrated very strong HbA1c-lowering and weight-reducing effects of tirzepatide compared with placebo and control drugs [133-139]
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Since the expansion of approved uses to include weight loss, these medications have become increasingly popular

Diabetes Care 43 (2), 487493 (2020)