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6,14 Furthermore, GLP-1 signaling indirectly enhances and restores the insulin signaling pathway in neurons, leading to a reduction in the phosphorylation of insulin receptor substrates and the burden caused by monomeric -synuclein

For patients planning pregnancy, semaglutide should be discontinued at least 2 months before a planned pregnancy due to its long half-life

GLP-1 receptor agonists: Beyond their pancreatic effects

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