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As this report aims to support clinicians in reviewing major mechanistic studies of the approved molecule tirzepatide, it does not include studies of other GIPRA/GLP-1RAs under investigation

Frias JP et al (2020) Efficacy and tolerability of tirzepatide, a dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes: A 12-week, randomized, double-blind, placebo-controlled study to evaluate different dose-escalation regimens

Another clinical study found reduced rates of alcohol use-related hospitalisations amongst patients being treated with Ozempic

Systematic tracking allows you to identify when a compound is working, when it is not, and when adjustments are needed

Learn about its and how it works with other medication youre taking

Consuming smaller, more frequent meals rather than three large meals prevents excessive stomach distension