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Because cardiovascular events are a major driver of health care costs in patients with diabetes, previously mentioned reductions in the incidence of major cardiovascular events associated with several GLP-1 receptor agonists have the potential to translate into health economic benefits (39)

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[DOI] [PubMed] [Google Scholar] 47.Heerspink H.J.L., Stefnsson B.V., Correa-Rotter R., Chertow G.M., Greene T., Hou F.-F., Mann J.F.E., McMurray J.J.V., Lindberg M., Rossing P., et al

However, several considerations cast doubt on the endocrine mechanism of the GLP-1