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It is important to recognise that pharmaceutical GLP-1 agonists are not cosmetic weight-loss drugs but prescription medications for specific medical conditions
Additionally, GLP-1 medications slow gastric emptying , which helps moderate the post-meal rise in blood glucose and promotes satiety
They also observed less response to GLP-1 in the pancreas and in the gut of these mice, indicative of GLP-1 resistance, yet there was no change in the expression of GLP-1 receptors in these tissues
In my clinical experience, I also see improvements in lipid panels and inflammation markers also
This triple agonism allows for an integrated modulation of key pathways regulating body weight and metabolic homeostasis
Semaglutide and heart failure: Updated meta-analysis
