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Description
Hypoglycemic agents with clear anti-tumor effects Metformin Metformin is among the most widely prescribed oral hypoglycemic agents in clinical practice
The challenge is that peptides are difficult to deliver orally
2024;7 doi: 10.1001/jamanetworkopen.2024.21305
Clinical trials measure outcomes around ~6872 weeks, showing the full effect of consistent treatment + lifestyle support
Dulaglutide is covalently linked to human immunoglobulin IgG 4 heavy chain molecules to reduce immunogenicity, enhance water solubility, and avoid degradation by DPP-4
(2020) see ref
