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Practices using a metabolic health EMR platform can embed BMI thresholds and comorbidity checklists directly into visit templates, reducing the risk that a physician forgets to document the severity classifier at point of care

Starting doses are typically lower for oral formulations (7 mg weekly equivalent), and dose escalation happens more gradually, meaning it takes longer to reach therapeutically optimal levels compared to injectable protocols that can reach target doses faster

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Table 2 outlines the prevalence of GI adverse events stratified by patient demographics and comorbidities among the study population