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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Koole C, et al

The HFD mice given low dose or high dose semaglutide alone had enlarged fatty livers that were more similar to the HFD control

To explore why this combination is critical, ACLM spoke with Chief Medical Officer and Internist for Aroga Lifestyle Medicine Jasdeep Saluja, MD, FRCPC, DipABLM, DipABOM, who chairs ACLMs GLP-1 Committee, about how he integrates lifestyle medicine into care for patients using GLP-1 medications

Indeed, the stimulatory effect of GLP-1(2836) on glycolysis and its inhibitory effect on FAO were consistent in all vascular cell types studied and under all experimental conditions

Many patients see improvements in these markers even before achieving their weight loss goals, suggesting direct beneficial effects of the medication itself
