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Glucagon-like peptide-1 (GLP-1) receptor agonists are a newer class of diabetes drugs that have the potential to double as weight loss drugs, widening their lucrative market potentials

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But access remains limited, even for patients covered by Medicaid, because of stringent prerequisites that must be satisfied before starting the drug.

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A Renewed Look at an Old Controversy Ever since GLP-1 receptor agonists (GLP-1 RAs) entered clinical practice for diabetes and obesity, their metabolic benefits have been undeniable

Among non-diabetic patients without chronic kidney disease (CKD), there was a minimal increase of 0.01 mg/dL to 0.02 mg/dL in serum creatinine in the months following initiation of semaglutide, liraglutide, or tirzepatide