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J Neurosurg 143:10371047, 2025 This multicenter propensity-matched cohort study examines the association between glucagon-like peptide-1 receptor agonist (GLP-1-RA) therapy and clinical, neurosurg

GLP-1 receptor agonists are the most talked-about drug class in medicine right now

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In the past seven years, the proportion of new, commercial patients who are rejected for a launch brand increased from 37% to 56%, such that more than half of the attempts to initiate a new treatment in 2022 were unfilled the first year

Administered as a subcutaneous weekly injection, it is a manifold single pharmacological agent that has the ability to significantly lower glucose levels, as well as improve insulin sensitivity, reduce weight and amend dyslipidemia favorably modifying the lipid profile

The trial was conducted in parallel in Japan, France, England, Mexico, Denmark, the USA and Germany as part of an international, randomized, double-blind study