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Animal studies suggest a very high margin of safetyrodents tolerated doses 100+ times higher than therapeutic doses without death

Flexibility & Core: Bonus Stability 10-Minute Core Blast: Lie on your back for 20 bicycle crunches (elbows to opposite knees), hold a 30-second plank (forearms on ground, body straight), and do 15 leg raises (lift legs to 90 degrees, lower slowly)

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10.1161/CIRCRESAHA.120.316710 48

Muscle cramps are not listed as a common side effect in FDA labeling for GLP-1 receptor agonists, and clinical trials have not shown significantly higher rates compared to placebo

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