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NLRP3 is also considered a key regulator of intestinal inflammation in humans, as exemplified by conditions such as Crohns disease

[DOI] [PubMed] [Google Scholar] 30.Nauck M.A., et al

To reduce potential underdose, this pen is recommended for patients requiring at least 20 units per day
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In moderate to severe IBD, intravenously administered NPs designed to selectively target inflamed intestinal tissue offer therapeutic potential [387, 396]