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An 8-week dose escalation regimen was employed at the start of treatment, with dose escalation (as tolerated) from 0.25 mg/week for 4 weeks to 0.5 mg for 4 weeks, followed by a maintenance dose of 1.0 mg/week throughout the remainder of the treatment period

With each milestone, results become more visible and encouraging

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Presented at the 2026 ADA Scientific Sessions, results showed weight loss up to 14.514.6%, HbA1c reduction up to 1.7 percentage points, and roughly 89% of participants reaching HbA1c below 7%

DOI: 10.1186/s12986-016-0153-3, Kanoski, S

This phenomenon, known as senescence, can be mitigated by enhancing mitochondrial fitness and physical capacity, which contribute to healthy aging