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It also has been documented that men with IIH are more likely to have symptoms of testosterone deficiency, such as erectile dysfunction and reduced libido (48)

The risk of upper gastrointestinal bleeding is rare with semaglutide alone, with no increased incidence in major clinical trials

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Did side effects remain manageable

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Different combinations or even larger cocktails of agonists and/or antagonists may turn out to be even more effective going forward