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Once-weekly formulations typically provide more stable plasma concentrations with lower peak levels compared to shorter-acting preparations, potentially reducing the intensity of gastrointestinal side effects

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These morphological and molecular adaptations were accompanied by improved insulin sensitivity and downregulation of inflammatory markers such as TNF- and IL-6 [11]

fibrosis reversal may take 1218 months or longer

References 1.Brennan PN, Tavabie OD, Li W, et al