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This clinician-led screening balances guideline-based criteria with individualized judgment to protect patients and optimize outcomes

The hesitation usually stems not from medical facts but from misconceptions and social stigmafears of complications or external judgment

doi: 10.1056/NEJMoa1603827

The LEADER trial for liraglutide and SUSTAIN-6 for semaglutide established cardiovascular benefit for that class

Diabetes Obes Metab 25(1):5667 Rosenstock J, Wysham C, Frias JP et al (2021) Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial

34 In human research, administration of prebiotic fiber has been associated with a significant decrease in hunger, significantly greater satiation after meals and increased plasma GLP-1 levels