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The therapeutic potential of GLP-1 receptor agonists in the management of hidradenitis suppurativa: a systematic review of anti-inflammatory and metabolic effects

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We know there's a vast majority of them that do not translate and the human evidence is still emerging but it is promising

Because peptides dont easily survive digestion, the pill is formulated at a much higher dose than the injection to account for the portion of the drug that is lost during digestion before the body can absorb it

The SELECT trial showed a 20% reduction in cardiovascular events among overweight or obese patients taking semaglutide

(Wegovy, another GLP-1, is FDA approved for weight loss.) GLP-1 is a naturally occurring hormone that tells the pancreas to release insulin needed to lower blood sugar levels