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The optimal dosage regimen is determined by the doctor

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Potentially severe side effects of Trulicity: Hypoglycemia Gastroparesis (stomach paralysis) Ileus (intestinal blockage) Gallbladder disease Kidney damage Pancreatitis Thyroid tumors (Trulicity carries a boxed warning of thyroid tumors after studies showed an increased risk in animals, but had unclear implications for humans) Allergic reactions Signs and symptoms of serious side effects may include severe abdominal pain, persistent nausea, vomiting, fever, dark urine, or signs of an allergic reaction

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This can affect their therapeutic effectiveness

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Dopamine (DA), a precursor for adrenaline and noradrenaline, is decreased in individuals with IBS (Mitsi and Zachariou, 2016) and psychological disorders, and it can regulate intestinal inflammation by inhibiting the NLRP3 inflammasome (Yan et al., 2015

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