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This allows them to enhance the first-phase insulin response , which is the precise, rapid release of insulin immediately after eatinga function often lost early in the development of metabolic dysfunction
Tirzepatide (Mounjaro / Zepbound): The Closest Competitor Tirzepatide is the closest competitor to Retatrutide in terms of mechanism and efficacy

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Tirzepatide activates both GLP1 and GIP receptors
