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Abstract Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad pharmacological potential

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This FDA-approved titration schedule was designed through clinical research to minimize gastrointestinal adverse effects while achieving therapeutic weight loss

Thus, the pooled and meta-analysis data suggest that GLP-1RA has a small, favorable effect on systolic BP in patients with T2DM

Insurers also increased use of prior authorization, which requires doctors to get plan approval before prescribing GLP-1s

doi: 10.1210/jc.2002-021545