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GLP-1 treatment protects endothelial cells from oxidative stress-induced autophagy and endothelial dysfunction

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Tirzepatide significantly improved cardiometabolic risk markers in adults with obesity and moderate to severe obstructive sleep apnea in the SURMOUNT-OSA phase 3 trials

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In biochemical and preclinical research systems, GLP-RT interacts with three class B G protein-coupled receptors that regulate metabolic signaling networks: GLP-1R, GIPR, and GCGR