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& Cusi, K

A 2025 substudy in adults with type 2 diabetes found that retatrutide significantly reduced fat mass and that its lean-mass loss proportion was similar to what has been seen in other obesity treatments

Nutritional deficiencies and muscle loss in adults with type 2 diabetes using GLP-1 receptor agonists: A retrospective observational study

Decisions regarding twice-daily (BID) or once-daily (QD) dosing are, therefore, critical to balance efficacy and the risk of adverse events

Just as is the case with any other injection, there may be a few side effects associated with GLP-1 injections

The SURMOUNT-1 trial, also in the New England Journal of Medicine, studied tirzepatide in adults with obesity or overweight without type 2 diabetes