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Does dry mouth mean I am dehydrated

Steady-state plasma concentrations are reached after roughly four weeks of once-weekly dosing, per the FDA label, so four weeks is not arbitrary

Part comes from diet and lifestyle choices

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Although experimental models have demonstrated that certain probiotic strains exert beneficial protective and anti-inflammatory effects, promising therapeutic options remain elusive, while dysbiosis, along with the emergence of various pathobionts and gut bacterial metabolites, may contribute to mild hepatic and systemic inflammation [58]

Its usually worst during the first few days after dose increases, particularly within 24 to 48 hours of injection