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GLP-1 activates the GLP-1R to stimulate adenylate cyclase (AC), increasing intracellular levels of cyclic AMP (cAMP) (Sandoval and DAlessio, 2015)

This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors
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Similar patterns may occur with pharmacological weight loss, though specific data for semaglutide are lacking
