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The most interesting thing about GLP-1 drugs and alcohol isn't that people drink less it's what shifts underneath

Hazard ratios for risk of any stroke with semaglutide versus placebo were 0.60 (95% CI, 0.370.99

Among people with pre-existing SUDs, initiation of GLP-1 receptor agonists was associated with reduced risk of SUD related emergency department visits (0.69 (0.61 to 0.78), NRD 8.92 (11.59 to 6.25)), SUD related hospital admissions (0.74 (0.65 to 0.85), NRD 6.23 (8.73 to 3.74)), and SUD related mortality (0.50 (0.32 to 0.79), NRD 1.52 (2.32 to 0.72)), and drug overdose (0.61 (0.42 to 0.88), NRD 1.49 (2.43 to 0.55)) and suicidal ideation or attempt (0.75 (0.67 to 0.83), NRD 9.95 (13.14 to 6.77))

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Retatrutide is studied in research settings because of its relationship with GLP-1, GIP and glucagon receptor pathways

This highly bioavailable form of magnesium chelate glycinate is less likely to cause loose stools in sensitive individuals than other forms of magnesium