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The medications decrease appetite and suppress hunger cravings by affecting the brains reward systems

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This multi-receptor strategy sets it apart from previous generations of weight loss drugs by addressing not just hunger and insulin regulation, but also energy expenditure and fat oxidation

doi: 10.3390/ijms23020739

These data suggest that GLP-1RAs may have unwanted oncogenic effects on receptor-positive NET subtypes (e.g., duodenal, gastric, and pancreatic NETs) and are less likely to affect NENs lacking the receptor (e.g., thyroid and ileal NETs)
