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doi: 10.1007/s40262-019-00756-2 [DOI] [PMC free article] [PubMed] [Google Scholar] 159.Hausner H, Derving Karsbol J, Holst AG, et al
Their rise has been nothing short of extraordinary
Rather than conducting a new meta-analysis, the authors synthesize findings from major randomized clinical trials, highlighting outcomes related to glycated hemoglobin (HbA1c), body weight reduction, major adverse cardiovascular events (MACE), and kidney function decline as reported in large cardiovascular outcomes trials (CVOTs), obesity randomized controlled trials, and early-phase clinical development studies
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Experiment 1: peripheral administration of GLP-1R agonists on water and food intake
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