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In a prospective observational study from Greece, adults with obesity treated with tirzepatide in routine clinical practice experienced rapid early reductions in body weight, waist circumference, and fat mass, with preservation of fat-free mass (Adamidis et al., 2025[1])
Some people cannot tolerate either at higher doses
These triggers can appear at any age and often change over time
People with a history of pancreatitis often require specialist decision-making (and may be advised to avoid)
