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This includes large countries such as India, Canada, China, Brazil and Turkey which make up 40% of the worlds population and an estimated 33% of the worlds population of adults living with obesityi (see Figure 1)

This was attributed to insulin deficiency and vomiting-induced acid loss and bicarbonate retention

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Therefore, the aim of this study was to examine the anti-inflammatory, analgesic, and anti-degradative effects in OA using in vitro and in vivo experiments