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I'd suggest pausing berberine for the first four to six weeks of semaglutide, specifically to let your GI system adjust to semaglutide before adding another compound with GI side effects

In a study involving 20 non-diabetic obese patients, participants were given either liraglutide - a GLP-1 agonist - or placebo for 8-weeks

Acknowledgements The authors thank the interview participants and survey respondents who contributed to this study

Avoid High-Risk NSAIDs : Certain NSAIDs, like aspirin or ibuprofen, may pose a higher risk of stomach issues

Additionally, some OTC alternatives may contain stimulants or unapproved compounds that can pose health risks, particularly for individuals with underlying medical conditions

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