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To put these results into context, it is important to keep in mind that Liraglutide, 3 mg, branded as Saxenda for weight loss, prompts a mean body weight decrease of 8% compared to 2.6% for placebo about half of what 2.4 mg semaglutide (Wegovy) achieved in the general obese population

Our initiation on our GLP-1 L/S basket and thematic primer can be found here: As of the one-year mark on 7/12/2024, the GLP-1 basket was up +85.12%

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The receptor pharmacology is classical: GLP-1R binding on pancreatic beta cells and extra-pancreatic tissues including CNS, stomach, and cardiovascular tissues, with Gs-adenylyl cyclase-PKA downstream signaling

Thursday, April 23, 12 2 pm ET : A free webinar, Domestic Violence and Brain Injury for Survivors and Caregivers , hosted by the Ohio Domestic Violence Network and Brain Injury Association of Ohio