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Adults in West Columbia with a BMI of 30 or higher, or 27 with related conditions such as high blood pressure, high cholesterol, or sleep apnea, might be excellent candidates for treatment

Gut (2017) 66(2):22634.10.1136/gutjnl-2015-309871 171 FlynnCRAlbaughVLCaiSCheung-FlynnJWilliamsPEBruckerRMet alBile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery

Early weight reduction is likely to be modest, and individual responses will vary considerably

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Treatment depends on the cause

In particular, a dual-action combination drug has been developed and approved for use, which is simultaneously an agonist of GLP-1 and GIP receptors tirzepatide (see Table 2)