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That gap of 10+ percentage points represents a fundamentally different outcome for many individuals
And several studies suggest that exenatide increased expression levels of BDNF in AD mice hippocampus and cortex (141, 203, 204)

One concern with any new treatment approach is tolerability, particularly for a population already dealing with complex health challenges

This was not observed in Phase 2 and has not been reported with GLP-1 or GLP-1/GIP agonists

Roberts VL, Stewart J, Issa M, et al

In an osteoarthritis model, a single liraglutide injection decreased synovitis and pain sensitivity, without affecting body weight
