semaglutide and trevogrumab REGN study showed that with combo therapy (semaglutide, trevogrumab, garetosmab), monkeys lost 1,400g body fat but gained 450g muscle. This alleviates the concerns of muscle loss and paves way for a Regeneron's COURAGE trial shows semaglutide
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Focus on staying hydrated, eating fiber-rich foods, and giving your body time to adjust
doi: 10.1210/er.2016-1078

The trials were originally met with limited enthusiasm since several extensive outcome trials had indicated that intensified diabetes therapy was not associated with cardiovascular benefit

Individual tolerance varies considerably

Burnham KP, Anderson DR
Taking semaglutide while breastfeeding isnt currently advised
