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Monitor portion sizes carefully

Ozempic Face refers to the visible facial volume loss (hollowing, sagging, thinning) that can accompany rapid or substantial weight loss whether from GLP-1 medications or other methods

Drug-induced CPP is rooted in classical Pavlovian conditioning and reflects a preference (or avoidance) for a context based on the contiguous pairing of the context with drug delivery
Side effects like nausea or GI symptoms may occur from semaglutide itself, not from interaction with metformin

doi: 10.1523/JNEUROSCI.5520-03.2004

Serious but rare adverse effects include pancreatitis, gallbladder disease, acute kidney injury (particularly with severe dehydration from vomiting or diarrhoea), and potential thyroid effects
