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As exenatide was the first widely used synthetic GLP-1R agonist in humans, much of the work examining the glucose dependence of GLP-1R-mediated insulin secretion was completed with exenatide
Off-Label Use: Critical Considerations Using GLP-1RAs for psychiatric conditions is considered off-label use
doi: 10.1161/circulationaha.119.045033, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 93
The next decade will be defined by the connection between access, science, and confidence, he says
That result is encouraging, but it was observational, so it shows an association rather than proof of prevention
Despite demonstrating the potential benefits of liraglutide in this pediatric group, the trial presents some key limitations
