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Description
The standard tirzepatide titration schedule from the FDA label is: 2.5mg for 4 weeks, then 5mg, 7.5mg, 10mg, 12.5mg, and 15mg, each step 4 weeks apart
Although preliminary data are encouraging, especially regarding the reduction of inflammation and body weight, open questions remain regarding the effects of these drugs on a longer time scale and on different patient subgroups
included at least one ICD code for T2D (Supplemental Table 1)

The most common are nausea, fatigue, and changes in bowel habits (like constipation or diarrhea)
The degree of improvement in the indices of liver damage was directly related to the dosage of semaglutide and greater for high doses

NT-proBNP, N-terminal probrain natriuretic peptide
