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(2) Estimate the absolute change in HbA1c, estimated glomerular filtration rate (eGFR), and cholesterol levels during 1year treatment with GLP1 RA compared with treatment with metformin, in subgroups by whether the patient had prediabetes or diabetes to evaluate realworld use

Quick Answer: Current clinical evidence does not show that weight loss injections cause cancer in humans, though FDA Boxed Warnings exist for thyroid C-cell tumors based on rodent studies

Specifically, it called for safety data from at least 500 patients with stage 3 or 4 CKD, 600 with established CVD, and 600 aged over 65

Support may include: Reviewing current medications and medical history

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