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Demographics of GLP-1 Users: Who Is Getting Treated GLP-1 users span diverse age groups and income levels, though early adopters skewed toward higher-income individuals with better healthcare access

In an uncontrolled study in people with T2D, liraglutide initially lowered eGFR (35), but this result was not confirmed in placebo-controlled studies that assessed mGFR and kidney hemodynamic function by gold-standard tracer methods (36)

Trial evidence supports significant reductions in body weight and waist circumference, both of which reflect fat loss

Triple agonists including retatrutide show exceptional promise based on remarkable weight loss and liver fat normalization in early trials, with dedicated MASH histology studies ongoing

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Grover SA, Kaouache M, Rempel P, et al