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Competing interests Nik Krajnc: has participated in meetings sponsored by, received speaker honoraria or travel funding from BMS/Celgene, Janssen-Cilag, Merck, Novartis, Roche and Sanofi-Genzyme and held a grant for a Multiple Sclerosis Clinical Training Fellowship Programme from the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)

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They also act on the appetite centers in the brain, significantly reducing hunger and what is often called food noise. The dual-action drug tirzepatide works on both GLP-1 and GIP receptors, often leading to even greater efficacy

doi: 10.1152/ajprenal.00527.2014 28 JiaY.ZhengZ.GuanM.ZhangQ.LiY.WangL.et al

Yang S, Zhao L, He W, Mi Y (2022) The effect of oral antidiabetic drugs on improving the endocrine and metabolic states in women with polycystic ovary syndrome: a systematic review and network meta-analysis

This dysbiosis is temporary and typically self-corrects as your gut microbiota rebalances over time
