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Description
Additional analyses were conducted at individual study level or pooled across 5 SURPASS trials
Methods Two separate observational cohort analyses were conducted using Optums de-identified Clinformatics Data Mart Database (CDM) and Komodo Healthcare Map (January 1, 2018 to September 30, 2022)
Dual-agonists such as GLP-1R/GIPR (e.g., Hengruis HRS9531) and triple-agonists such as GLP-1R/GIPR/GCGR (e.g., United Laboratories UBT251) represent the next technological wave, aiming for superior weight loss and broader metabolic benefits
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Millions of people are turning to GLP-1s for weight loss, but many are surprised to learn that the medication alone isn't enough
Individual response varies based on metabolism, genetics, and starting dose
