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Additionally, several key clinical trial readouts delivered compelling data across multiple indications, for example (see Figure 1): Semaglutide: STEP-HFpEF (functional benefits in HFpEF), STEP-9 (pain reduction in knee osteoarthritis), STEP-10 (reversion to normoglycaemia in pre-diabetic, obese patients), ESSENCE (resolution of MASH, improvement in fibrosis) Tirzepatide: SUMMIT (risk reduction in HFpEF outcomes

Retrospective data showed that GLP-1 receptor agonist use was associated with a 51% reduction in colorectal cancer odds among patients with inflammatory bowel disease.

Next up: glucagon-like peptide 1 receptor agonists, known colloquially (and identified here) as GLPs

For optimal results, it's recommended to take two capsules daily with food, maintaining consistent use for at least 3-6 months

Simply apply a patch to clean, dry skin and continue your daily activities with confidence

Suitable for adults who need daily reinforcement, being particularly useful for individuals on weight loss plans, severe calorie restriction diets, or who suffer from reduced appetite