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These intestinal side effects are typically most pronounced during dose escalation and tend to improve as the body adjusts

This work was supported by the Funds of National Natural Science Foundation of China (82060728), Guizhou Provincial Science and Technology Department (MS [2025-380], Thousand Talents Program), Talents of Guizhou Science and Technology Platform [2021]1350-009, Zunyi Science and Technology Bureau (HZ-2023-173, HZ-2023-09, [2024] No

L-type calcium channels open more readily, allowing more calcium to flow into the cell

doi: 10.1038/npp.2010.105 120 LiY.PerryT.KindyM

4 Sodhi M, Rezaeianzadeh R, Kezouh A, Etminan M