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Phase 3 Results (REIMAGINE-2, Feb 2026): HbA1c reduction of up to 1.91 points, outperforming semaglutide alone Weight loss of up to 14.2% at 68 weeks in adults with type 2 diabetes and obesity In weight-management evaluation, diabetics achieved ~15.7% weight loss vs 3.1% with placebo Regulatory update: Novo Nordisk filed for FDA approval (Dec 2025) for weight management, supported by the REDEFINE clinical program

Moreover, to account for possible confounders, adjusted ORs (mainly based on age, sex, body mass index [BMI], diabetes) were pooled and analyzed

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