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Landmark studies show that early tight glycemic control slows the progression and development of diabetic autonomic neuropathy (DAN) and microvascular complications (Fig

Inhibits glucagon release , which helps reduce the production of glucose in the liver

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10.1002/oby.20674 27 ColmersI
Weight Loss Outcomes Associated With Semaglutide Treatment for Patients With Overweight or Obesity." Published in JAMA Network Open, Accessed on November 13, 2023 at Nature Medicine Journal

GLP-1 is also believed to participate in weight loss after bariatric surgery which brings food more rapidly into the distal small intestine