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Weight Loss Injections Medications like GLP-1 receptor agonists (e.g., liraglutide or semaglutide) mimic natural hormones that regulate appetite and improve blood sugar control

The mechanism is that GLP-1 exerts its glucagon inhibitory effect in human pancreatic islets through an intrinsic (non-paracrine) PKA-dependent effect mediated by the activation of the few GLP-1Rs present in the plasma membrane of -cells, which ultimately inhibits P/Q-type Ca2+ channels (Ramracheya et al., 2018)

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Semaglutide is a GLP-1 receptor agonist that mimics the hormone GLP-1 naturally released after eating

IGF-1 plays a key role in energy metabolism and body composition regulation, achieving weight loss without muscle loss