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With the right precautions and open communication, most people on GLP-1 therapy can manage the risk of serious kidney problems and dehydration-related complications.

The companies that generate the best returns from the LOE cycle are those that see further ahead than their competitors identifying P.IV opportunities before competitors file, anticipating LOE events before they reach consensus estimates, and securing API supply chain relationships before generic launch day

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Animal studies show more promising results, particularly around reducing liver fat, which can indirectly improve lipid profiles, but this hasnt been firmly established in humans yet

For people using these drugs for blood sugar control, the loss of effectiveness carries much more immediate risk than for someone who might only see slower or less weight loss

It's a biology problem